Date: Oct 27, 2017. Mark Daly: Dovetail Genomics – Building the Best Genomes on Earth

Mark Daly is the Director of Sales at Dovetail Genomics LLC

A contiguous and accurate genome assembly is a crucial first step in fully understanding the biology of any organism.  A high-quality genome assembly will make any downstream analyses, like gene annotation, synteny, comparative genomics and population genetics far easier and more reliable.

Dovetail Genomics is the leading service provider for high quality genome assemblies. To date, they have completed more than 400 projects, spanning many classes of organisms from plants to reptiles, amphibians, fish, mammals, birds, insects and more.

Using two complementary scaffolding methods, Chicago and Dovetail Hi-C, they are dramatically increasing the contiguity and accuracy of genome assemblies, enabling true, full-chromosome-length scaffolding. This talk will provide an update on their most current technologies.  Mark will profile several customer projects and discuss how improvements in their assemblies led to better science and new discoveries.

Date: Oct 27, 2017
Time: 10:00 AM
Location: Weill hall, Room 226

Date: Dec 7, 2015. Susan Strickler: Long read assembly and annotation strategies for complex plant genomes

Susan Strickler is a Research Associate in the Mueller lab at the Boyce Thompson Institute on Cornell University campus.

Plant genome assembly can be notoriously difficult due to such challenges as heterozygosity, polyploidy, and repeats.  The long read technology provided by PacBio sequencing can help to overcome some of these obstacles to result in more complete and accurate assembly and annotation.  In this talk, I will discuss de novo genome assembly tools and methods for processing PacBio genome and transcriptome data to generate high quality plant genomes and gene models.

Date: Dec 07, 2015
Time: 11:00 AM
Location: Weill hall, Room 221

Slides

Date: Mar 10, 2014. Aureliano Bombarely: Insights into Plant Genome Sequence Assembly

Aureliano Bombarely is a Research Associate at the Doyle Lab in the Plant Biology Department. He was formerly with the Sol Genomics group at BTI. Please see here for recent publications.

Recent developments in genome assembly tools and algorithms will be presented. There will be particular focus on challenges associated with assembling polyploid plant genomes. Methods to assess quality and completeness in order to compare multiple assemblies will also be covered

Date: Mar 10, 2014
Time: 4:00 PM
Location: Weill hall, Room 321

Slides