Jeff Glaubitz is a Senior Research Associate and the Project Manager of Panzea - the NSF Maize Diversity Project.
The NSF project Biology Of Rare Alleles In Maize And Its Wild Relatives (Ed Buckler, PI) is combining the power of population genetic and molecular models with quantitative genetics to elucidate the relative contributions of rare versus common alleles to phenotypic variation and evolution. We are taking advantage of recent advances in high-throughput genotyping and phenotyping methodologies to identify the key biological attributes of variants (genome annotations) that will allow us to better predict the functional effects of rare alleles in Zea. This information will then be used to accelerate crop improvement either through more accurate genomic selection or via future genome editing approaches. We hope to enhance the effectiveness of plant breeding by improving our ability to identify, predict, and select on the effects of rare variants, both deleterious and beneficial. In this talk I will give an overview of the biological goals of this project and the various bioinformatic tools that are being developed to achieve these goals, with an emphasis on TASSEL.
Date: April 20, 2015
Time: 11:00 AM
Location: Weill hall, Room 321
Slides
Showing posts with label Maize. Show all posts
Showing posts with label Maize. Show all posts
Monday, April 13, 2015
Thursday, February 26, 2015
Date: Mar 2, 2015. Minghui Wang: Genome-wide crossover distribution in the population of maize B73 and Mo17
Minghui Wang is a Postdoctoral Associate at the BRC Bioinformatics Facility on campus.
Crossovers (COs) are essential for the accurate segregation of homologous chromosomes at the first meiotic division. However, CO are not evenly distributed across genome. Their number and location are tightly regulated. Here, we report a detailed, genome-wide characterization of the rate and localization of COs in maize, in male and female meiosis.
Date: Mar 2, 2015
Time: 11:00 AM
Location: Weill hall, Room 321
Slides
Crossovers (COs) are essential for the accurate segregation of homologous chromosomes at the first meiotic division. However, CO are not evenly distributed across genome. Their number and location are tightly regulated. Here, we report a detailed, genome-wide characterization of the rate and localization of COs in maize, in male and female meiosis.
Date: Mar 2, 2015
Time: 11:00 AM
Location: Weill hall, Room 321
Slides
Tuesday, January 27, 2015
Date: Feb 2, 2015. Zehong Ding: Comparison of leaf gradient transcriptomics in multiple C3 and C4 species
Zehong Ding is a Postdoctoral Associate at the BRC Bioinformatics Facility on campus.
Transferring C4 photosynthesis into C3 crops has been proposed as one of the most promising ways to increase the yield ceiling and hence global productivity. To better understand the function of C4 photosynthesis, and to identify candidate genes that associated with C4 pathway, comparative transcriptomes were conducted along a leaf developmental gradient in maize, viridis, sorghum and rice. In total 478 C4 candidate genes were identified. Besides the classical C4 genes, many function well characterized genes that associated with light reaction, starch and sucrose metabolism, hormone, TFs, and transporters were included. These findings will provide important insights into the gene differentiation between C3 and C4 species. In addition, the C4 candidate genes that identified in our approach would be a useful gene resource that could be used for C4 engineering of C3 crops.
Date: Feb 2, 2015
Time: 11:00 AM
Location: Weill hall, Room 321
Slides
Transferring C4 photosynthesis into C3 crops has been proposed as one of the most promising ways to increase the yield ceiling and hence global productivity. To better understand the function of C4 photosynthesis, and to identify candidate genes that associated with C4 pathway, comparative transcriptomes were conducted along a leaf developmental gradient in maize, viridis, sorghum and rice. In total 478 C4 candidate genes were identified. Besides the classical C4 genes, many function well characterized genes that associated with light reaction, starch and sucrose metabolism, hormone, TFs, and transporters were included. These findings will provide important insights into the gene differentiation between C3 and C4 species. In addition, the C4 candidate genes that identified in our approach would be a useful gene resource that could be used for C4 engineering of C3 crops.
Date: Feb 2, 2015
Time: 11:00 AM
Location: Weill hall, Room 321
Slides
Tuesday, April 22, 2014
Date: Apr 28, 2014. Robert Bukowski: HapMap3: large-scale genotyping for Zea mays
Robert Bukowski is a Senior Research Associate at the BRC Bioinformatics Facility on campus.
The maize HapMap project, currently at its third release, focuses on capturing allelic variation, including rare alleles, across a highly diverse set of maize germplasm. It is a part of ongoing effort in the pan-zea community to identify variants responsible for complex trait variation. I will present computational techniques we use to characterize genotypes of about 1,000 maize lines from Illumina whole-genome sequencing data.
Date: Apr 28, 2014
Time: 11:00 AM
Location: Weill hall, Room 221
Slides
The maize HapMap project, currently at its third release, focuses on capturing allelic variation, including rare alleles, across a highly diverse set of maize germplasm. It is a part of ongoing effort in the pan-zea community to identify variants responsible for complex trait variation. I will present computational techniques we use to characterize genotypes of about 1,000 maize lines from Illumina whole-genome sequencing data.
Date: Apr 28, 2014
Time: 11:00 AM
Location: Weill hall, Room 221
Slides
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